This story is from November 07, 2025
THIS overlooked blood test could expose the real cause of heart attacks in people who seem perfectly healthy
Most health-conscious people closely track their cholesterol, blood sugar, and blood pressure, but cardiologists are now highlighting another vital yet often ignored heart health factor, Lipoprotein(a), or Lp(a). This lesser-known blood component can silently raise the risk of heart attacks and strokes, even in people with normal cholesterol levels. US-based cardiologist Dr Dmitry Yaranov, known online as @heart_transplant_doc, has been spreading awareness about it. In his viral post titled “The one blood test you wish you knew about sooner,” he called Lp(a) the test few have ever heard of, often overlooked by doctors, trainers, and even cardiologists unless they are forward-thinking about long-term cardiovascular health.
According to the reports, Lipoprotein(a) is a type of low-density lipoprotein (LDL), commonly known as “bad cholesterol.” However, Lp(a) behaves differently from standard LDL. In addition to contributing to plaque buildup in the arteries, it can make blood clots more resistant to breakdown and promote inflammation that destabilises arterial plaque. This dangerous combination significantly heightens the risk of heart attacks, strokes, aortic valve disease, and other cardiovascular issues, even when routine cholesterol results seem perfectly normal.
Dr Yaranov points out that one in five individuals may have high Lp(a) levels. Unlike typical cholesterol, which can be influenced by diet or exercise, Lp(a) is primarily genetic. Therefore, lifestyle changes alone cannot lower it. This means that even people who appear fit, eat healthily, and avoid smoking may unknowingly carry a higher risk of cardiovascular disease if their Lp(a) levels are elevated.
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Unlike regular cholesterol or lipid profile tests that need to be monitored periodically, the Lp(a) test usually only needs to be done once in your lifetime. Because Lp(a) levels are genetically determined, they remain relatively stable throughout life. The normal Lp(a) level should be below 30 milligrams per decilitre (mg/dL). Higher readings may suggest an increased risk of cardiovascular and vascular disease.
Despite its importance, this test is not routinely included in standard cholesterol screenings, meaning patients often need to specifically request it. Dr Yaranov shared that he has encountered patients who appeared exceptionally healthy: marathon runners, non-smokers, and clean eaters who nevertheless suffered severe cardiac events due to undetected high Lp(a) levels.
Researchers are still investigating effective treatments for reducing Lp(a). As of now, no medication has been approved by the US Food and Drug Administration specifically to target elevated Lp(a). However, cardiologists recommend that individuals with high Lp(a) manage other modifiable risk factors aggressively.
This includes controlling LDL cholesterol, blood pressure, and blood sugar, along with maintaining a healthy weight and avoiding smoking. While these measures may not lower Lp(a) directly, they can significantly reduce the overall burden on the cardiovascular system while research continues to advance toward targeted therapies.
Heart disease remains one of the leading causes of death globally, often striking without obvious warning signs. Dr Yaranov’s message is clear: prevention starts with awareness. “Don’t wait for symptoms. Prevent the crisis before it happens. Know your numbers. Ask about Lp(a). That one test could save your life,” he urged.
Also Read | Gotu Kola benefits: How THIS ancient ‘herb of longevity’ supports brain, kidney, and liver detoxification
How lipoprotein(a) increases heart disease risk even in healthy individuals
According to the reports, Lipoprotein(a) is a type of low-density lipoprotein (LDL), commonly known as “bad cholesterol.” However, Lp(a) behaves differently from standard LDL. In addition to contributing to plaque buildup in the arteries, it can make blood clots more resistant to breakdown and promote inflammation that destabilises arterial plaque. This dangerous combination significantly heightens the risk of heart attacks, strokes, aortic valve disease, and other cardiovascular issues, even when routine cholesterol results seem perfectly normal.
Dr Yaranov points out that one in five individuals may have high Lp(a) levels. Unlike typical cholesterol, which can be influenced by diet or exercise, Lp(a) is primarily genetic. Therefore, lifestyle changes alone cannot lower it. This means that even people who appear fit, eat healthily, and avoid smoking may unknowingly carry a higher risk of cardiovascular disease if their Lp(a) levels are elevated.
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ID@undefined __se__tag_icon ico_copytxtCopy MSID__se__tag_icon ico_embedSocialIcons_instagram Caption not available.
Why the Lp(a) test is a one-time check that many people overlook
Unlike regular cholesterol or lipid profile tests that need to be monitored periodically, the Lp(a) test usually only needs to be done once in your lifetime. Because Lp(a) levels are genetically determined, they remain relatively stable throughout life. The normal Lp(a) level should be below 30 milligrams per decilitre (mg/dL). Higher readings may suggest an increased risk of cardiovascular and vascular disease.
Despite its importance, this test is not routinely included in standard cholesterol screenings, meaning patients often need to specifically request it. Dr Yaranov shared that he has encountered patients who appeared exceptionally healthy: marathon runners, non-smokers, and clean eaters who nevertheless suffered severe cardiac events due to undetected high Lp(a) levels.
Managing high Lp(a) through lifestyle and overall heart health control
Researchers are still investigating effective treatments for reducing Lp(a). As of now, no medication has been approved by the US Food and Drug Administration specifically to target elevated Lp(a). However, cardiologists recommend that individuals with high Lp(a) manage other modifiable risk factors aggressively.
This includes controlling LDL cholesterol, blood pressure, and blood sugar, along with maintaining a healthy weight and avoiding smoking. While these measures may not lower Lp(a) directly, they can significantly reduce the overall burden on the cardiovascular system while research continues to advance toward targeted therapies.
Heart disease remains one of the leading causes of death globally, often striking without obvious warning signs. Dr Yaranov’s message is clear: prevention starts with awareness. “Don’t wait for symptoms. Prevent the crisis before it happens. Know your numbers. Ask about Lp(a). That one test could save your life,” he urged.
Also Read | Gotu Kola benefits: How THIS ancient ‘herb of longevity’ supports brain, kidney, and liver detoxification
Comments (1)
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Dinesh JainMost Interacted
196 days ago
Something which cannot be corrected need not be monitored. Value of Lp(a) will have meaning for insurers only as they may refuse t...Read More
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